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Dolser-MR Tablet
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Dolser-MR Tablet

Manufactured byKenn Pharmaceuticals
ContainsMetaxalone (400 mg) + Diclofenac (50 mg)
Description
Dolser-MR Tablet is a pain killer medication composed of Metaxalone and Diclofenac. It is used to reduce pain occurring due to muscle spasms (contractions). Dolser-MR Tablet stops the release of certain chemical messengers responsible for pain and muscle stiffness. Dolser-MR Tablet relieves pain and swelling due to musculoskeletal conditions but does not cure them. Dolser-MR Tablet shows side effects like drowsiness, dizziness, nausea, vomiting, stomach pain, stomach upset, loss of appetite and diarrhoea. Contact your doctor if any side effects persist for a long period of time or if the condition worsens. Avoid driving or operating heavy machines while on treatment with this medicine. Dolser-MR Tablet should ideally be taken with food to avoid stomach problems. Take this medicine as advised by your doctor. For the ease of remembering, take it at around the same time every day. Dolser-MR Tablet should be used with caution if you have a history of liver or kidney problems. Avoid using this medicine if you are previously allergic to it. Dolser-MR Tablet is not recommended in children below 12 years of age. Consult your doctor before taking this medicine if you are pregnant or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Dolser-MR Tablet

  • Constipation
  • Skin rash
  • Ringing or buzzing in the ears
  • Dizziness and Drowsiness
  • Stomach pain
  • Nausea and Vomiting
  • Diarrhoea
  • Headache
  • Nervousness
  • Chest pain
  • Loss of appetite
  • Shortness of breath
  • Black or tarry stools
  • Difficult or painful urination
  • Itching
  • Cough
  • Stomach upset
  • Heart burn

Uses of Dolser-MR Tablet

What is it prescribed for?

  • Acute musculoskeletal pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The pain-relieving effect of Dolser-MR Tablet can be observed within 30 minutes of taking the tablet.
  • How long do the effects of this medicine last?
    Dolser-MR Tablet may remains active in the body for up to 8 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with Dolser-MR Tablet may increase the side effects such as dizziness, headache, gastrointestinal bleeding, weakness, fatigue, etc.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported. for Dolser-MR Tablet.
  • Can this medicine be taken during pregnancy?
    Dolser-MR Tablet is not recommended during pregnancy due to the risk of serious side effects to your foetus.
  • Can this medicine be taken while breast-feeding?
    It is not known whether Dolser-MR Tablet passes into the breast milk. It is recommended that you consult your doctor before taking this tablet while breastfeeding.

Allergy

Avoid taking Dolser-MR Tablet if you are allergic to it. If you notice any symptoms such as a skin rash, itching/swelling (especially in the face, lips, tongue, etc.), dizziness, breathing difficulty, etc., seek immediate medical attention.

Active peptic ulcer

Peptic ulcers are the sores (blisters) that are formed in the linings of the stomach and intestine. Dolser-MR Tablet is known to damage the mucosal lining in the stomach and intestine causing severe internal bleeding. Avoid the use of Dolser-MR Tablet if you have an active peptic ulcer or are suspected of having it.

Drug-induced haemolytic anemia

Haemolytic anemia is a condition in which the red blood cells are destroyed rapidly. Drug-induced haemolytic anemia may occur when a medicine triggers the body's defence system to attack its own red blood cells. Dolser-MR Tablet is not recommended for use in people with drug-induced hemolytic anaemia or other anaemia.

Coronary Artery Bypass Surgery (CABG)

Coronary Artery Bypass Surgery is a procedure that restores normal blood flow to your heart muscle by diverting the flow of blood around the blocked artery. Dolser-MR Tablet is not recommended for relieving pain after heart surgery as it increases the risk of heart attack or stroke.
Warnings for special population

Pregnancy

Dolser-MR Tablet is not recommended during pregnancy due to the risk of serious side effects to your foetus.

Breast-feeding

It is not known whether Dolser-MR Tablet passes into the breast milk. It is recommended that you consult your doctor before taking this tablet while breastfeeding.
General warnings

Effect on heart

Prolonged use of Dolser-MR Tablet may cause serious side effects in persons with heart troubles. Your doctor will periodically monitor your heart function and vital signs while you are on this medication.

Gastro-intestinal effects

Long term use of Dolser-MR Tablet can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration, and perforation (holes) in the lining of the stomach or intestinal wall may occur.

Use in elderly

Dolser-MR Tablet should be used with caution in elderly people (above 65 years of age) due to the increased risk of serious side effects.

Use in children

The safety and efficacy of Dolser-MR Tablet have not been clinically established in children under the age of 12 years, hence it is recommended that Lysoflam-MR Tablet should not be used in children.

Sedation

The use of Dolser-MR Tablet may cause dizziness and drowsiness. Hence, avoid driving vehicles and operating heavy machines after taking this medicine.

Fluid retention and oedema

Dolser-MR Tablet causes oedema (accumulation of body fluid in the feet and legs). Your blood pressure, electrolyte levels, and heart function will be closely monitored when you are on treatment with this medicine.

Skin allergies

Dolser-MR Tabletmay cause serious skin allergies in rare cases. Signs and symptoms like rashes, hives (itchy eruptions with burning pain), or other allergic symptoms should be reported to your doctor immediately.

Kidney Impairment

Dolser-MR Tablet should be used with caution in mild to moderate kidney problems. In such conditions, excessive use of the medicine may lead to further kidney damage.

Missed Dose

In case you forget to take the scheduled dose of Dolser-MR Tablet take it as soon as you remember. If it is almost time for the next dose, skip the forgotten dose. Do not double the dose.

Overdose

Never take more than the prescribed dose of Dolser-MR Tablet. In case you have taken an overdose of this medicine, seek emergency medical attention.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with Dolser-MR Tablet may increase the side effects such as dizziness, headache, gastrointestinal bleeding, weakness, fatigue, etc.
Interaction with Medicine

Amitriptyline

Methotrexate

Ramipril

Tramadol

Adefovir

Apixaban

Ketorolac

Disease interactions

Asthma

Dolser-MR Tablet may cause bronchospasm (narrowing of the airways in your lungs). Therefore, it should be used with caution if you have asthma.

Impaired kidney function

Dolser-MR Tablet may cause serious damage to your kidney if used for a long time. Your doctor will closely monitor your kidney function while you are on this medication.

Heart Disease

Dolser-MR Tablet increases the risk of heart attack and stroke. If you have heart issues, do not use this medicine without your doctor’s prescription.

Anaemia

Dolser-MR Tablet should not be used if you have any form of anaemia. Inform your doctor beforehand so that he may choose the best treatment option for you.

Liver Disease

Dolser-MR Tablet can cause severe damage to the liver. If you have liver problems, use this medicine only on your doctor’s recommendation.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Dolser-MR Tablet should be taken with food to avoid gastric irritation. Do not chew or crush the tablet in the mouth. Never take more than the prescribed dose. Take this medicine at around the same time daily. Dolser-MR Tablet along with physical therapy and rest helps to relieve pain in conditions such as strains, sprains, and other muscle injuries. Dolser-MR Tablet can make you drowsy and dizzy, hence avoid driving, operating heavy machines, or consuming alcohol while on this medication.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
Dolser-MR Tablet consists of Metaxalone and Diclofenac. It helps to reduce pain and improves muscle movement. Metaxalone blocks the nerve signals (pain sensation) from reaching the brain. Diclofenac works by reducing the formation of certain substances in the body that are responsible for causing pain and inflammation (swelling).
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Skeletal muscle relaxants, Non-steroidal anti-inflammatory agent combinations

Schedule

Schedule H

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https://pubchem.ncbi.nlm.nih.gov/compound/Diclofenac>

Pubchem.ncbi.nlm.nih.gov. 2021. Metaxalone. [online] Available at: < [Accessed 16 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/metaxalone>

Drugs, H., 2021. Metaxalone: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 16 July 2021].

https://medlineplus.gov/druginfo/meds/a682010.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 4 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/13217s036lbl.pdf>

Dailymed.nlm.nih.gov. 2021. DailyMed - METAXALONE tablet. [online] Available at: < [Accessed 4 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=de3448df-4ca1-44ec-bad1-486549cddf64>

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https://www.medicines.org.uk/emc/product/4515/smpc#gref>
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Information on this page was last updated on 25 Aug 2021

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