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Dolokind 75 MG Injection

Manufactured byMankind Pharmaceuticals Ltd.
ContainsDiclofenac
Description
Dolokind 75 MG Injection is a painkiller used to relieve pain and swelling associated with osteoarthritis (tender and painful joints due to wear down of protective cartilage between the ends of the bones), rheumatoid arthritis (a type of arthritis affecting the small joints of the body), ankylosing spondylitis (pain and stiffness of bones of the spine), low back pain, neck pain, etc. It is also used in post-operative patients for pain relief. Dolokind 75 MG Injection blocks the formation of chemical substances in the body that cause swelling and pain. Dolokind 75 MG Injection shows side effects like nausea, pain at the site of injection, and diarrhoea. Most of these side effects do not require medical attention and resolve with time. However, if any of these side effects persist or worsen, consult your doctor at the earliest. Inform the doctor if you have known allergies to this medicine. Do not indulge in any work that requires mental focus as you may feel dizzy after receiving this medicine. Avoid alcohol consumption as it may increase the risk of dizziness or sleepiness. Dolokind 75 MG Injection should be administered in a hospital setting by healthcare professionals. It is prescribed when oral administration is not possible or for faster pain relief when the pain is severe or unbearable. Do not try to self-administer. Long term use of this medicine may cause serious complications such as stomach bleeding and kidney disease. Dolokind 75 MG Injection will be prescribed by your doctor in a suitable dose based on your clinical condition. Discuss the potential risks and all the medications that you are taking with your doctor before receiving this medicine. Inform the doctor if you are pregnant, planning a pregnancy, or are breastfeeding.

Side effects

Major & minor side effects for Dolokind 75 MG Injection

  • Constipation
  • Diarrhoea
  • Nausea and vomiting
  • Skin rash
  • Tinnitus
  • Pain at the injection site

Uses of Dolokind 75 MG Injection

What is it prescribed for?

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Mild to moderate pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Dolokind 75 MG Injection may start to work immediately after injection.
  • How long do the effects of this medicine last?
    The average time for which Dolokind 75 MG Injection stays in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while receiving Dolokind 75 MG Injection due to the increased risk of serious side effects such as severe stomach and intestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
  • Is this a habit forming medicine?
    Dolokind 75 MG Injection has no habit-forming tendencies.
  • Can this medicine be taken during pregnancy?
    Dolokind 75 MG Injection is not recommended in pregnancy as it may cause miscarriage or may affect the development of the heart of your foetus. Discuss all the potential benefits and risks with your doctor before starting the therapy.
  • Can this medicine be taken while breast-feeding?
    Dolokind 75 MG Injection may pass into the breastmilk in small amounts. If you are breastfeeding, inform your doctor beforehand.

Allergy

Do not receive Dolokind 75 MG Injection if you have a known allergy to this medicine. Seek medical attention if you come across any allergic reactions such as a skin rash, hives (itchy, painful eruptions that sting), swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Coronary artery bypass surgery

Coronary artery bypass graft (CABG) is a surgical procedure that diverts the blood from narrowed or blocked vessels in the heart to improve its blood supply. Dolokind 75 MG Injection is not recommended for use before, during, or after a coronary artery bypass graft surgery as it may cause heart failure.

NSAID-induced asthma

Non-steroidal anti-inflammatory drugs (NSAIDs)-induced asthma is an allergic condition of the respiratory system that may occur after you take an NSAID. These medicines narrow the airway and provoke mucous secretion in the airway, causing severe breathing difficulty. Dolokind 75 MG Injection is not recommended for use in this condition.
Warnings for special population

Pregnancy

Dolokind 75 MG Injection is not recommended in pregnancy as it may cause miscarriage or may affect the development of the heart of your foetus. Discuss all the potential benefits and risks with your doctor before starting the therapy.

Breast-feeding

Dolokind 75 MG Injection may pass into the breastmilk in small amounts. If you are breastfeeding, inform your doctor beforehand.
General warnings

Gastro-intestinal toxicity

Dolokind 75 MG Injection may cause damage to the stomach and intestine, especially on prolonged use. This risk is specifically higher in patients with a history of gastrointestinal diseases. Consult your doctor about the potential risks before taking this medicine.

Skin allergies

Dolokind 75 MG Injection may cause skin allergies in some patients. Inform your doctor immediately if you develop signs and symptoms such as rashes, hives, or other allergic symptoms.

Water retention

Dolokind 75 MG Injection may cause water retention (majorly in lower limbs) in some patients. Your doctor may suggest tests to monitor your blood pressure, electrolyte levels, and heart function based on your clinical condition.

Driving or operating machines

Dolokind 75 MG Injection may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving or operating machines if you experience any of these symptoms during treatment with this medicine.

Use in elderly

Dolokind 75 MG Injection should be used with caution in elderly patients due to the increased risk of kidney and liver impairment. Your doctor will generally start treatment with lower doses to check for your tolerance to this medicine. Your kidney and liver function may have to be closely monitored.

Impaired liver function

Dolokind 75 MG Injection should be used with caution if you have liver problems. This medicine may cause an increase in the values of one or more liver enzymes. Your doctor may suggest tests like LFT (liver function test) to check if the medicine is showing any negative effects on your liver.

Missed Dose

Since Dolokind 75 MG Injection is usually administered by a qualified healthcare professional in the hospital setting, the likelihood of a missed dose is very low.

Overdose

Since Dolokind 75 MG Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving Dolokind 75 MG Injection due to the increased risk of serious side effects such as severe stomach and intestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
Interaction with Medicine

Methotrexate

Ramipril

Apixaban

Ketorolac

Cyclosporine

Disease interactions

Kidney diseases

If you already have kidney disease, using Dolokind 75 MG Injection for a prolonged period can potentially worsen the condition of your kidney. It is recommended that you get your kidney function monitored regularly as per your doctor’s guidance.

Heart diseases

Receiving Dolokind 75 MG Injection for a prolonged period may increase the risk of a heart attack. Your doctor will periodically suggest tests to ensure the regular functioning of your heart.
Food interactions
Information not available.
Lab interactions
Information not available.
Dolokind 75 MG Injection is usually administered in the hospital setting under the supervision of a qualified healthcare professional. Use this medicine as directed by your doctor. Long-term use may lead to serious complications such as stomach bleeding and kidney disease. Do not drive or operate the machine if you experience dizziness and drowsiness. Avoid alcohol consumption while on treatment with this medicine. Inform your doctor if you have a known allergy to this medicine. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Dolokind 75 MG Injection works by blocking the formation of certain chemical substances in the body that are responsible for causing pain and swelling.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Nonsteroidal anti-inflammatory agents

Schedule

Schedule H

Medicines.org.uk. 2021. AKIS 75mg/ml solution for injection - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 12 July 2021].

https://www.medicines.org.uk/emc/product/9399/smpc>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 12 July 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022396lbl.pdf>

Mri.cts-mrp.eu. 2021. [online] Available at: < [Accessed 26 July 2021].

https://mri.cts-mrp.eu/human/downloads/CZ_H_0938_004_FinalPL_2of2.pdf>
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Information on this page was last updated on 26 Aug 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.