Cinnarizine

Description

Cinnarizine is a medicine that belongs to the category of antihistaminic medications. It is used to treat problems associated with the inner ear and the brain. This medicine is used to treat dizziness and sickness associated with motion sickness.

Side effects

Major & minor side effects for Cinnarizine

  • Drowsiness
  • Weight gain
  • Indigestion
  • Nausea or Vomiting
  • Stomach discomfort and pain
  • Excessive sweating
  • Unusual tiredness and weakness
  • Headache
  • Dry mouth
  • Twitching and unusual movement of muscles
  • Yellowing of skin and eyes
  • Excessive salivation
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Depressed mood
  • Muscle stiffness and trembling

Uses of Cinnarizine

What is it prescribed for?

  • Motion sickness
  • Vertigo and vestibular disorders
  • Heart and blood vessel disorder
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within an hour of oral administration.
  • Duration of effect
    The effect of this medicine lasts for 6-8 hours in most cases.
  • Safe with alcohol?
    Avoid or limit the uptake of alcohol while using this medicine. It is advised to refrain from driving a vehicle or operating a heavy machinery while taking this medicine.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Consult your doctor and discuss the benefits and risks associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use by a breastfeeding woman unless absolutely necessary. Consult your doctor and discuss the benefits and risks associated with the use of this medicine. It is advised to discontinue breastfeeding while the medicine is being taken.

Allergy

This medicine is not recommended for use if you have a known history of allergy to Cinnarizine or any other component present along with it.

Depression

This medicine is not recommended for use if you suffer from depression or any other depressive disorders.

Porphyria

This medicine is not recommended for use in patients suffering from a rare genetic condition affecting the blood and the skin.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Consult your doctor and discuss the benefits and risks associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use by a breastfeeding woman unless absolutely necessary. Consult your doctor and discuss the benefits and risks associated with the use of this medicine. It is advised to discontinue breastfeeding while the medicine is being taken.
General warnings

Depression

Use of this medicine may cause lack of interest, low mood, sleep disturbances in some patients. It should be administered with caution in patients with an active/past instance of depression.

Drowsiness

Use of this medicine may cause drowsiness and sleepiness in some patients. It is advised to not perform any activity requiring a high level of mental alertness while taking this medicine.

Liver/kidney disease

This medicine should be used with caution in a patient having a liver disease or impairment of normal liver/kidney function.

Glaucoma

This medicine should be used with caution in patients having glaucoma. Report any instance of disturbance in vision, pain or dryness of eyes to the doctor immediately.

Pediatric use

This medicine is not recommended for use in children below 5 years of age.

Use in elderly

This medicine should be used with caution in the elderly as the risk of adverse effects are significantly high.

Fall in blood pressure

Use of high doses of this medicine may cause a fall in blood pressure and hence should be used with caution in patients suffering from hypotension.

Galactose intolerance

This medicine should not be used if you suffer from a genetic disorder causing intolerance to galactose or other sugars.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

Overdose

Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include drowsiness, tiredness, increased heart rate, mild agitation etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Use of alcohol while taking this medicine may cause an excessive amount of drowsiness, sleepiness.

Instructions

Avoid or limit the uptake of alcohol while using this medicine. It is advised to refrain from driving a vehicle or operating a heavy machinery while taking this medicine.
Interaction with Medicine

Amitriptyline

Tramadol

Chlorpromazine

Diazepam

Disease interactions

Parkinson's disease

This medicine should be used with caution in patients suffering from Parkinson's disease. It should be used only when the potential benefits outweigh the risks involved with use.

Porphyria

This medicine is not recommended for use if you have a genetic disorder of the blood and skin (Porphyria). The risk of adverse effects are significantly high and hence your doctor may suggest a suitable alternative.
Food interactions
Information not available.
Lab interactions

Skin sensitivity test

Report the use of this medicine to the doctor before a skin sensitivity test. This medicine may interfere with the procedure and may give false negative results. Use of this medicine should stop at least 4 days before the test is conducted.
Take Cinnarizine as instructed by the doctor. This medicine can be taken after food. Take this medicine 2 hours prior to starting the travel. Do not take more than the recommended dose of this medicine.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts on the vomiting center in the brain to prevent the sensation of vomiting.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Antiemetic/antivertigo agents

Schedule

Schedule H

[Internet]. 2017 [cited 17 May 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/30284

Cinnarizine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 17 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00568

Cinnarizine | C26H28N2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 17 May 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1547484

[Internet]. 2017 [cited 16 November 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/30284

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Information on this page was last updated on 16 Nov 2017

Disclaimer

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