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Calmese 2 MG Injection

Manufactured byThemis Medicare Ltd.
ContainsLorazepam
Description
Calmese 2 MG Injection is an anticonvulsant medicine, which is used to relieve the symptoms of anxiety and seizures. This medicine may increase the risk of habit-forming tendency if taken for a long duration or at larger doses. Do not stop abruptly taking this medicine as it may cause withdrawal symptoms like convulsions, behavioral disorders, tremors, etc.

Side effects

Major & minor side effects for Calmese 2 MG Injection

  • Drowsiness
  • Blurred vision
  • Confusion
  • Dry mouth
  • Headache
  • Constipation
  • Weakness
  • Rapid weight gain
  • Shaking of hands or feet

Uses of Calmese 2 MG Injection

What is it prescribed for?

  • Anxiety
  • Status Epilepticus
  • Preanesthesia
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed intravenously within 5 minutes and intramuscularly within 15-30 minutes after administration of the.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 6-8 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    Habit-forming tendencies were reported in some cases especially if the usage is for an extended period of time. A gradual withdrawal of the drug i.e. decrease in dosing over a period of time is suggested in such cases.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to lorazepam, other benzodiazepines, or any other inactive ingredients present in the formulation.

Narrow-angle glaucoma

This medicine is not recommended for use in patients with a known history of narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Severe liver disease

This medicine is not recommended for use in patients with severe liver disease due to the increased risk of worsening of the patient's condition.

Myasthenia gravis

This medicine is not recommended for use in patients with myasthenia gravis due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings

Depression

This medicine is not recommended in the patients with known case of depression due to the worsening if symptoms.

Suicidal tendencies

This medicine may cause suicidal behavior in some patients. This risk is especially higher on the prolonged usage of the medicine. Patients should be monitored closely for any changes in behavior and mood; any such changes should be reported to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Use in elderly

This medicine should be administered with caution in elderly patients since the risk of severe adverse effects is significantly high. Suitable adjustments in dose quantity and safety monitoring may be required in such cases.

Withdrawal symptoms

This medicine may cause withdrawal symptoms if the usage is stopped abruptly. This risk is especially higher after prolonged usage of this medicine. The treatment should be withdrawn gradually under the close supervision of your doctor. Do not stop the use of this medicine without consulting your doctor.

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in obese patients

This medicine should be used with caution in obese patients with careful monitoring of symptoms. An increase in dosing intervals might be necessary in some cases. Close monitoring of the patient's condition, while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. However, it is advised to contact the doctor immediately if you miss a scheduled dose of this medicine.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Cetirizine

Metoclopramide

Opioids

Ramipril

Atenolol

Disease interactions

Closed-Angle Glaucoma

This medicine is not recommended for use in patients with a known history of closed-angle glaucoma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Impaired kidney function

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Impaired liver function

This medicine should be used with extreme caution in patients suffering from liver diseases due to an increase in the risk of serious adverse effects including coma. Close monitoring of liver function tests is necessary while receiving this medicine. Report any symptoms of confusion or jaundice to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Respiratory disorders

This medicine should be used with caution in patients with a known history of respiratory disorders since it may worsen the patient's condition. Close monitoring of lung function is recommended for such patients. Replacement with a suitable alternative treatment may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Causes sleepiness

How it works
It works by binding to certain chemicals in the brain and helps in relieving the symptoms.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Benzodiazepine derivatives

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2020 [cited 10 March 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/018140s028lbl.pdf

[Internet]. Medicines.org.uk. 2020 [cited 10 March 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.5473.pdf

[Internet]. Pfizer.ca. 2020 [cited 10 March 2020]. Available from:

https://www.pfizer.ca/sites/default/files/201909/Lorazepam_PM_E_230606_22Aug2019.pdf

Lorazepam - DrugBank [Internet]. Drugbank.ca. 2020 [cited 10 March 2020]. Available from:

https://www.drugbank.ca/drugs/DB00186
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Information on this page was last updated on 28 May 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.