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Azathioprine 50 MG Tablet
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Azathioprine 50 MG Tablet

Manufactured byAlkem Laboratories Ltd.
ContainsAzathioprine
Description
Azathioprine 50 MG Tablet is an immuno-suppressant medicine (medicine that suppresses the activity of the immune system). It is used after organ transplantation to prevent your body from rejecting the transplanted organ due to the body's immune activity. It is also used in severe cases of rheumatoid arthritis (pain and swelling in the small joints due to abnormal immune activity). Azathioprine 50 MG Tablet shows side effects like nausea, vomiting, diarrhoea, loss of appetite, stomach pain, upset stomach, low blood cell count, etc. Moreover, it may suppress your immunity and you may be at risk of acquiring other infections. Consult your doctor if any of these side effects persist or worsen. Avoid taking this medicine if you are allergic to it. Azathioprine 50 MG Tablet should be taken with food to avoid stomach discomfort. Your doctor will decide the dose and duration of treatment based on the type of transplant or severity of your condition. Do not stop taking this medicine without consulting your doctor, as it may increase the chances of organ rejection by your body and worsen your condition. Azathioprine 50 MG Tablet is unsafe for use during pregnancy. Inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding. Consult your doctor if you are taking any other medicines or have any other medical conditions.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Azathioprine 50 MG Tablet

Azithioprine 50 MG Tablet
Alkem Laboratories Ltd.
Imuza 50 MG Tablet
Panacea Biotec Ltd.
Zymurine 50 MG Tablet
Zydus Cadila
Azapure 50 mg Tablet
Intas Pharmaceuticals Ltd.
AZR 50 mg Tablet
Ipca Laboratories Pvt. Ltd.

Side effects

Major & minor side effects for Azathioprine 50 MG Tablet

  • Fever with chills
  • Sore throat
  • Stomach pain
  • Loss of appetite
  • Muscle and joint pain
  • Nausea and Vomiting
  • Hair loss
  • Low blood cell count
  • Diarrhoea

Uses of Azathioprine 50 MG Tablet

What is it prescribed for?

  • Prevention of organ transplant rejection
  • Rheumatoid Arthritis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Azathioprine 50 MG Tablet to show its action is not known.
  • How long do the effects of this medicine last?
    The time duration for which Azathioprine 50 MG Tablet remains active in your body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Azathioprine 50 MG Tablet has no habit-forming tendency.
  • Can this medicine be taken during pregnancy?
    Azathioprine 50 MG Tablet is unsafe for use during pregnancy.
  • Can this medicine be taken while breast-feeding?
    Azathioprine 50 MG Tablet is not recommended for use while breastfeeding.

Allergy

Avoid taking Azathioprine 50 MG Tablet if you are allergic to it. Allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.

Severe liver disease

Azathioprine 50 MG Tablet is broken down in the liver. An impaired liver is unable to break down this medicine, leading to its accumulation in the liver. Hence, Azathioprine 50 MG Tablet is not recommended for use if you have severe liver problems as it may cause further liver damage.
Warnings for special population

Pregnancy

Azathioprine 50 MG Tablet is unsafe for use during pregnancy.

Breast-feeding

Azathioprine 50 MG Tablet is not recommended for use while breastfeeding.
General warnings

Malignancy

Azathioprine 50 MG Tablet should be used with caution as it may increase the risk of lymphoma (cancer of the cells of the lymph system, a part of the immune system that keeps body fluid levels in balance and defends the body against infections) and other cancers, particularly of the skin.

Blood cell count

Azathioprine 50 MG Tablet may cause severe bone marrow suppression (a condition in which there is low production of blood cells) and lead to a low blood cell count. Your doctor may monitor your blood count closely while you are taking this medicine.

Serious infections

Azathioprine 50 MG Tablet may suppress the activity of the immune system and increase the risk of infections.

Renal dysfunction

Azathioprine 50 MG Tablet may accumulate in the body if you have impaired kidney function. Hence it should be used with caution if you have kidney problems. Your doctor may suggest tests to monitor your kidney functions periodically and recommended dose adjustments based on your clinical condition.

Missed Dose

If you miss a dose of Azathioprine 50 MG Tablet, take the missed dose as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention in case of an overdose with Azathioprine 50 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Warfarin

Live attenuated vaccines

Ramipril

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Azathioprine 50 MG Tablet should be taken with food to avoid stomach discomfort. Do not break, chew, or crush the tablet. Avoid taking more or less than the prescribed dose. Take this medicine for the recommended duration. Azathioprine 50 MG Tablet suppresses the immune activity in your body. Hence avoid contact with people who have a cold, flu, or other contagious illness. Inform your doctor if you have any signs of infection such as a fever, chills, flu symptoms, sore throat, weakness, etc.). Inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Azathioprine 50 MG Tablet works by decreasing the body's immune activity. Thus it prevents the immune system from attacking the transplanted organ or joints.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Other immunosuppressant

Schedule

Schedule H

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Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 30 November 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/016324s034s035lbl.pdf>

Stewart, M., 2021. Azathioprine (Imuran). [online] Patient.info. Available at: <o/medicine/azathioprine-azapress-imuran> [Accessed 30 November 2021].

https://patient.inf

Drugs, H., 2021. Azathioprine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 30 November 2021].

https://medlineplus.gov/druginfo/meds/a682167.html>

Medicines.org.uk. 2021. Azathioprine 50 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 30 November 2021].

https://www.medicines.org.uk/emc/product/3301/smpc#PHARMACOKINETIC_PROPS>
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Information on this page was last updated on 24 Dec 2021

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