Home >
Medicine Info >
Atrest 25 MG Tablet
Loading interface...

Atrest 25 MG Tablet

Manufactured byCentaur Pharmaceuticals Pvt. Ltd.
ContainsTetrabenazine
Description
Atrest 25 MG Tablet is used in the treatment of chorea (abnormal, jerky, or involuntary movements) associated with Huntington’s disease, an inherited condition in which the nerve cells in the brain become damaged. This medicine works by reducing the level of certain chemicals that cause abnormal movements. Atrest 25 MG Tablet shows some side effects such as headache, nausea, vomiting, depression, restlessness, body pain, tiredness, etc. Consult your doctor if any of these side effects persist or worsen. Avoid taking this medicine if you are allergic to it. Also, avoid performing activities that require mental focus such as driving vehicles or operating machines, as this medicine can make you feel drowsy. Atrest 25 MG Tablet may be taken with or without food. The dose and duration of the treatment will be determined by your doctor based on the severity of your condition. Do not stop taking this medication without consulting your doctor, as your symptoms may become worse. Atrest 25 MG Tablet is not recommended for use in children below the age of 18 years. Inform your doctor about all your current medications and pre-existing medical conditions before taking this medicine. This will help your doctor adjust the dose to avoid side effects. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
QUICK LINKS:
Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Atrest 25 MG Tablet

  • Fatigue
  • Depression
  • Drowsiness
  • Headache
  • Shortness of breath
  • Anxiety
  • Nausea and vomiting
  • Body pain
  • Chills and fever
  • Cough
  • Loss of balance control
  • Nasal congestion
  • Slurred speech
  • Sneezing
  • Sore throat
  • Loss of appetite
  • Restlessness
  • Difficult or painful urination
  • Trouble in speaking
  • Dizziness

Uses of Atrest 25 MG Tablet

What is it prescribed for?

  • Huntington's disease
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Atrest 25 MG Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The effect of Atrest 25 MG Tablet lasts for 16-24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Atrest 25 MG Tablet due to the increased risk of side effects.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Atrest 25 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Atrest 25 MG Tablet is not recommended for use during pregnancy unless absolutely necessary. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Atrest 25 MG Tablet is not recommended for use while breastfeeding.

Allergy

Avoid taking Atrest 25 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Liver impairment

Atrest 25 MG Tablet is not recommended if you have liver problems as this medicine is broken down in the liver. If you have impaired liver function, it may cause an accumulation of this medicine in the body, resulting in toxicity.

Monoamine oxidase inhibitors (MAOI)

MAOIs (monoamine oxidase inhibitors) are a class of medications used to treat depression and other mental health conditions. Avoid taking Atrest 25 MG Tablet with MAOIs or within two weeks after discontinuing MAOIs, as it can lead to life-threatening complications.

Active Suicidal Tendency

Atrest 25 MG Tablet may increase the risk of suicidal thoughts. Hence, it is not recommended for use if you have active suicidal tendencies and uncontrolled depression.
Warnings for special population

Pregnancy

Atrest 25 MG Tablet is not recommended for use during pregnancy unless absolutely necessary. Hence, consult your doctor if you are pregnant.

Breast-feeding

Atrest 25 MG Tablet is not recommended for use while breastfeeding.
General warnings

Driving vehicles and operating machines

Atrest 25 MG Tablet may cause drowsiness. Hence, avoid performing activities that require high mental alertness like driving vehicles or operating machines if you feel drowsy after taking this medicine.

Dysphagia

Atrest 25 MG Tablet should be used with caution if you have any conditions that may cause dysphagia (difficulty in swallowing). This medicine may cause dysphagia and further worsen your condition.

Hyperprolactinemia

Hyperprolactinemia means you have higher-than-normal levels of prolactin (a type of hormone) in your blood. In some cases, Atrest 25 MG Tablet may cause elevated prolactin concentrations in the blood. therefore, it should be used with caution if you have a history of breast cancer. Also, a chronic increase in prolactin levels may increase the risk of osteoporosis (weak and brittle bones).

Orthostatic hypotension

Atrest 25 MG Tablet may cause orthostatic hypotension (a sudden drop in blood pressure while suddenly getting up from a sitting or a lying position), which can lead to dizziness or fainting. To avoid this, stand up slowly from a sitting or lying position.

Use in children

Atrest 25 MG Tablet is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.

Neuroleptic Malignant Syndrome (NMS)

Neuroleptic malignant syndrome (NMS) is a rare but life-threatening reaction that can occur in response to certain medications. It is characterised by symptoms such as very high fever, muscle rigidity, altered mental status, sweating, etc. Atrest 25 MG Tablet should be used with caution as it may cause neuroleptic malignant syndrome in some cases.

Parkinsonism

Parkinsonism refers to a group of neurological conditions that cause difficulty with movements. The symptoms include tremors, slow movement, impaired speech, or muscle stiffness. Atrest 25 MG Tablet should be used with caution as it may trigger or aggravate such conditions.

Depression

Atrest 25 MG Tablet should be used with extreme caution as it may cause depression and increased suicidal thoughts. Consult your doctor immediately if you experience changes in mood and behaviour or develop thoughts of self-harm.

Missed Dose

Take the missed dose of Atrest 25 MG Tablet as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose of Atrest 25 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Atrest 25 MG Tablet due to the increased risk of side effects.
Interaction with Medicine

Metoprolol

Isocarboxazid

Phenelzine

Mefloquine

Deutetrabenazine

Disease interactions

QT prolongation

QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Atrest 25 MG Tablet should be used with caution as it may cause QT prolongation. It is not recommended for use if you have any clinical condition or taking any medication known to cause QT prolongation.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Atrest 25 MG Tablet as instructed by the doctor. Do not break, chew, or crush the tablet. Swallow as a whole with plenty of water. Avoid taking more or less than the recommended dose. Take it at the same time every day for the ease of remembering. Be careful while standing up from a sitting or lying position to avoid feeling dizzy. Consult your doctor if your symptoms do not improve, or if they get worse. Consult your doctor immediately if you experience changes in mood and behaviour or develop thoughts of self-harm.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Atrest 25 MG Tablet works by decreasing the levels of certain chemicals in the body that cause abnormal movements.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Vesicular monoamine transporter type 2 inhibitor (VMAT-2)

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2022. DailyMed - TETRABENAZINE tablet. [online] Available at: < [Accessed 7 April 2022].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=acf78d97-fca5-49aa-8683-6db7396da72f>

Medicines.org.uk. 2022. Tetrabenazine 25 mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 7 April 2022].

https://www.medicines.org.uk/emc/product/8961>

Lundbeck.com. 2022. [online] Available at: < [Accessed 7 April 2022].

https://www.lundbeck.com/upload/us/files/pdf/Products/Xenazine_PI_US_EN.pdf>

Accessdata.fda.gov. 2022. [online] Available at: < [Accessed 7 April 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021894lbl.pdf>

Centaurpharma.com. 2022. Centaur Pharmaceuticals Pvt Ltd – India. [online] Available at: < [Accessed 7 April 2022].

http://www.centaurpharma.com/newwebsite/downloads/ATREST.pdf>
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 8 Apr 2022

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.