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Atazor-R Tablet

Manufactured byEMCURE PHARMACEUTICALS LTD
ContainsAtazanavir (300 mg) + Ritonavir (100 mg)
Description
Atazor-R Tablet is a combination of Atazanavir and Ritonavir. It is an antiviral medicine used for the treatment of human immunodeficiency virus (HIV) infection (a condition that occurs when the virus attacks the immune system and interferes with your body's ability to fight infections or diseases). Atazor-R Tablet will not cure HIV infection, but it will delay the progression of a chronic, potentially life-threatening condition known as acquired immunodeficiency syndrome (AIDS) and other HIV-related conditions. This medicine works by preventing the virus from multiplying. Atazor-R Tablet shows some side effects like nausea, vomiting, stomach pain, diarrhoea, headache, heartburn, dizziness, drowsiness, change in taste, weakness, trouble sleeping, etc. Consult your doctor if they bother you for a longer time or worsen. Do not take this medicine if you are allergic to it. Atazor-R Tablet should be taken with food. Take it in the dose and duration prescribed by your doctor. Do not take more than the recommended dose. Take it every day at the same time to maintain a consistent level of this medicine in your blood. Do not discontinue this medication without consulting your doctor, as it may worsen your condition. Atazor-R Tablet may not be suitable for everyone. Inform your doctor if you have heart, liver, or kidney problems, diabetes (high blood sugar levels), or any other health conditions. Also, inform your doctor about all your ongoing medications to avoid undesired effects. Atazor-R Tablet is unsafe for use during pregnancy. Consult your doctor if you are breastfeeding. If you have an HIV infection, it is not recommended to breastfeed, as the Human immunodeficiency virus (HIV) may transfer to the baby through breastmilk.

Side effects

Major & minor side effects for Atazor-R Tablet

  • Redness of the skin especially on the face and neck
  • Headache
  • Weight change
  • Confusion
  • Acid or sour stomach
  • Change in sense of taste
  • Sleepiness or unusual drowsiness
  • Mood or mental changes
  • Tender, swollen glands in the neck
  • Skin Rash
  • Sweating
  • Stomach pain
  • Diarrhoea
  • Dry mouth
  • Nausea and Vomiting
  • Weakness
  • Heartburn

Uses of Atazor-R Tablet

What is it prescribed for?

  • HIV infection
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Atazor-R Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Atazor-R Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Atazor-R Tablet.
  • Can this medicine be taken during pregnancy?
    Atazor-R Tablet may be used during pregnancy if clearly needed. If you are pregnant, consult your doctor to understand the potential risks and benefits of taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Atazor-R Tablet is not recommended for use while breastfeeding. Also, women with HIV infection are not recommended to breastfeed as the Human immunodeficiency virus (HIV) can be passed to the baby through breastmilk.

Allergy

Avoid taking Atazor-R Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Drug interaction

CYP3A or UGT1A1 are liver enzymes responsible for the breakdown of various medicines such as Alfuzosin, Amiodarone, Rifampin, Irinotecan, Triazolam, Midazolam, Cisapride, Simvastatin, Lovastatin, Indinavir, Sildenafil, Voriconazole, Ranolazine, Lurasidone, Pimozide, Colchicine, Ergotamine, etc., in the liver. Atazor-R Tablet is not recommended for use if you are receiving medicines that are highly dependent on CYP3A or UGT1A1 enzymes for their breakdown in the liver. Combined use may increase the risk of alteration in the blood levels of these medications, which may cause serious and life-threatening reactions.

Moderate to severe live impairment

Atazor-R Tablet is not recommended for use if you have moderate to severe liver problems, as this medicine may cause liver toxicity and further worsen your condition.
Warnings for special population

Pregnancy

Atazor-R Tablet may be used during pregnancy if clearly needed. If you are pregnant, consult your doctor to understand the potential risks and benefits of taking this medicine.

Breast-feeding

Atazor-R Tablet is not recommended for use while breastfeeding. Also, women with HIV infection are not recommended to breastfeed as the Human immunodeficiency virus (HIV) can be passed to the baby through breastmilk.
General warnings

Fat Redistribution

Atazor-R Tablet should be used with caution as it may cause fat gain or fat loss in the body. It may result in central obesity, buffalo hump (excess fat behind the neck), peripheral wasting (difficulty in moving an arm or leg or making any movement), facial wasting (fat loss in the cheeks and temples), breast enlargement, and cushingoid appearance (extra fat build up on the sides of the face and weight gain). Consult your doctor if you have any concerns.

Pancreatitis

Pancreatitis refers to the swelling of the pancreas, a gland that produces chemical substances which help in digestion and regulation of blood sugar. Atazor-R Tablet should be used with caution as it may cause pancreatitis. The risk is especially higher if you have a history of pancreatitis.

Immune reconstitution syndrome

Changes in your immune system can occur when you start taking Atazor-R Tablet. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. It may cause an exaggerated response making the symptoms of infection worse. Inform your doctor if you develop any new symptoms after starting treatment with Atazor-R Tablet.

Nephrolithiasis and Cholelithiasis

Atazor-R Tablet should be used with caution as it may cause Nephrolithiasis (kidney stones) and/or Cholelithiasis (gallstones).

Increase in cholesterol and fats levels

Atazor-R Tablet should be used with caution as it may cause an increase in cholesterol and fats levels in the blood. Your doctor may suggest tests to periodically monitor your lipid (fats) levels in the blood while you are taking this medicine.

Missed Dose

Take the missed dose of Atazor-R Tablet as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Contact your doctor in case of an overdose of Atazor-R Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Cisapride

Erythromycin

Fluoxetine

Loperamide

Midazolam

Cyclosporine

Lovastatin

Alprazolam

Disease interactions

Diabetes

Diabetes is a condition in which your blood sugar levels are increased. Atazor-R Tablet should be used with caution if you have diabetes as it may alter your blood sugar levels. Monitor your blood sugar levels regularly while you are taking this medicine.

Bleeding disorders

Haemophilia is an inherited bleeding disorder in which the blood does not clot properly. Atazor-R Tablet should be used with caution if you have haemophilia due to the increased risk of excessive bleeding.

Heart Disease

QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Atazor-R Tablet may cause QT prolongation hence, it should be used with caution if you have heart problems.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Atazor-R Tablet exactly as instructed by your doctor. Do not take in larger or smaller quantities than recommended. Your doctor may suggest tests to monitor your liver function and lipid (fats) levels during treatment with this medicine. This medicine may cause redistribution and accumulation of body fat in different parts of your body, such as below your neck, upper back, breasts, or around the stomach. It may also cause loss of body fat from your legs, arms, and face. Consult your doctor if you have any concerns.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Atazor-R Tablet works by stopping the human immunodeficiency virus (HIV) from multiplying.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Protease inhibitors, Antiviral agents

Schedule

Schedule H

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https://medlineplus.gov/druginfo/meds/a603019.html>

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https://medlineplus.gov/druginfo/meds/a696029.html>

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Information on this page was last updated on 1 Mar 2022

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