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Amlozaar (5/25 mg) Tablet
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Amlozaar (5/25 mg) Tablet

Manufactured byMicro Labs Ltd.
ContainsAmlodipine (5 mg) + Losartan (25 mg)
Description
Amlozaar (5/25 mg) Tablet is a combination of Amlodipine and Losartan. It is an anti-hypertensive medicine used for the treatment of high blood pressure. Amlozaar (5/25 mg) Tablet relaxes your heart muscles and widens the blood vessels. This decreases blood pressure and makes it easier for your heart to pump blood throughout your body. Amlozaar (5/25 mg) Tablet shows common side effects like headache, drowsiness, dizziness, swelling of feet and ankles, tiredness and an upset stomach. Most of these side effects do not require medical attention and disappear with time. If these symptoms worsen, consult your doctor. Amlozaar (5/25 mg) Tablet can be taken with or without food. Do not self-medicate or stop taking the medicine without your doctor's recommendation as it can lead to withdrawal symptoms. Be careful while standing up from a sitting or lying down position as this medicine may sometimes cause dizziness. Avoid taking Amlozaar (5/25 mg) Tablet with alcohol and grapefruit juice as it can cause dizziness. Amlozaar (5/25 mg) Tablet is not recommended if you have liver and kidney problems or have high potassium levels in your blood. Amlozaar (5/25 mg) Tablet is not recommended for use in children below 6 years, pregnant women and breastfeeding women unless prescribed by your doctor.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Amlozaar (5/25 mg) Tablet

  • Stomach pain
  • Chills
  • Difficulty or painful urination
  • Back pain
  • Weakness in arms, hands, legs or feet
  • Swelling of ankles or feet
  • Difficulty in breathing
  • Dizziness
  • Increased heartbeat
  • Redness of face, neck, arms and chest
  • Muscle pain

Uses of Amlozaar (5/25 mg) Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    After taking Amlozaar (5/25 mg) Tablet, the blood pressure will gradually decrease in 4-8 hours.
  • How long do the effects of this medicine last?
    Amlozaar (5/25 mg) Tablet on average can be effective for up to 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol during treatment with Amlozaar (5/25 mg) Tablet. Do not perform activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Amlozaar (5/25 mg) Tablet.
  • Can this medicine be taken during pregnancy?
    Avoid Amlozaar (5/25 mg) Tablet in pregnancy as it may affect your developing foetus. If you are pregnant or planning a pregnancy, consult your doctor.
  • Can this medicine be taken while breast-feeding?
    It is not known whether Amlozaar (5/25 mg) Tablet pass into the breastmilk. Inform your doctor if you are breastfeeding while taking this medicine.

Allergy

Avoid taking Amlozaar (5/25 mg) Tablet if you are allergic to it. Seek medical attention if you notice symptoms such as skin rash, hives (painful eruptions that itch and sting), swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Aliskiren

Aliskiren (a blood pressure reducing medicine) is a first-line medicine used in the treatment of hypertension. Taking Amlozaar (5/25 mg) Tablet and Aliskiren together is not recommended as it may lead to kidney damage, increase in your blood pressure and hyperkalaemia (high potassium levels in the blood). This may cause other side effects such as irregular heartbeat, muscle paralysis, heart attack, etc. This risk is especially higher in the elderly population, in people with diabetes and kidney problems.
Warnings for special population

Pregnancy

Avoid Amlozaar (5/25 mg) Tablet in pregnancy as it may affect your developing foetus. If you are pregnant or planning a pregnancy, consult your doctor.

Breast-feeding

It is not known whether Amlozaar (5/25 mg) Tablet pass into the breastmilk. Inform your doctor if you are breastfeeding while taking this medicine.
General warnings

Hyperkalemia

Amlozaar (5/25 mg) Tablet may lead to hyperkalaemia (increase in the potassium levels in your body) by preventing the excretion of potassium from the kidneys. Avoid potassium-rich foods or supplements while you are on this medication. Your doctor will suggest tests to regularly monitor your potassium levels. Your doctor may also adjust the dose of this medicine based on your clinical condition.

Use in children

Amlozaar (5/25 mg) Tablet is not recommended for use in children below 6 years of age as the safety and efficacy data are not clinically established.

Myocardial infarction and angina

Myocardial infarction (MI) is also known as a heart attack. It occurs due to permanent damage to the heart muscle. Angina is chest pain or discomfort caused by a lack of oxygen-rich blood to your heart muscle. Amlozaar (5/25 mg) Tablet should be used with caution in such conditions, especially while starting the treatment or increasing the dose because it may worsen the symptoms of myocardial infarction or angina.

Impaired liver function

Use Amlozaar (5/25 mg) Tablet with caution if you have liver problems. This medicine is broken down in your liver. Having liver problems may increase the accumulation of this medicine in your body which may damage your liver further. Your doctor will suggest tests to regularly monitor your liver function. They may also adjust the dose of the medicine as per requirements.

Aortic stenosis

Aortic Stenosis is the narrowing of the valve of the aorta (the largest blood vessel that branches off from your heart). Amlozaar (5/25 mg) Tablet should be used with extreme caution if you have aortic stenosis due to the increased risk of hypotension (low blood pressure). It is recommended that you regularly monitor your blood pressure while taking this medicine. Your doctor may adjust the dose of the medicine as per requirements.

Driving and operating machines

Amlozaar (5/25 mg) Tablet may cause dizziness or drowsiness. Avoid performing activities that require mental alertness like driving vehicles or operating machines if you experience any of these symptoms while taking this medicine.

Kidney impairment

Amlozaar (5/25 mg) Tablet should be used carefully if you have kidney problems like renal artery stenosis (narrowing of the arteries that carry blood to the kidneys) and/or volume depletion (excess loss of salt and fluid leading to reduced fluid volume). Your doctor will suggest tests to regularly monitor your kidney function while taking this medicine in such conditions.

Missed Dose

If you missed a dose of Amlozaar (5/25 mg) Tablet take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume at the scheduled time. Do not double your dose to make up for the missed one.

Overdose

Never take more than the dose prescribed by your doctor. If you have accidentally taken an overdose of Amlozaar (5/25 mg) Tablet, contact your doctor immediately for overdose treatment.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol during treatment with Amlozaar (5/25 mg) Tablet. Do not perform activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Carbamazepine

Itraconazole

Lithium

Rifampicin

Insulin

Nonsteroidal anti-inflammatory medicines

Disease interactions

Congestive heart failure

Congestive heart failure occurs when your heart muscle is not able to pump blood normally. Amlozaar (5/25 mg) Tablet should be used with caution if you have congestive heart failure as it may increase the risk of severe hypotension (low blood pressure) and acute kidney damage. It is recommended that you regularly monitor your blood pressure while you are taking this medicine. Your doctor will suggest tests to monitor your kidney function while on treatment with this medicine.

Severe hypotension or cardiogenic shock

Amlozaar (5/25 mg) Tablet should be taken with caution in conditions like cardiogenic shock (a major condition where the heart suddenly stops pumping blood to the body) or if you have severe hypotension (low blood pressure) due to increased risk of heart failure. It is recommended that you closely monitor your blood pressure. Your doctor may adjust the dose of the medicine depending on your clinical condition.
Food interactions
Grapefruit juice may decrease the effect of Amlozaar (5/25 mg) Tablet. Hence, avoid consuming grapefruit juice while taking this medicine.
Avoid taking high potassium-containing food or potassium supplements with Amlozaar (5/25 mg) Tablet as it may cause an increase in the potassium levels in your blood. Consult your doctor if you have symptoms such as weakness, irregular heartbeat, confusion, tingling sensation or feeling of heaviness in the legs.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Amlozaar (5/25 mg) Tablet orally with or without food. Do not crush, break or chew the tablet. Take it at the same time every day. Avoid taking more or fewer doses than that prescribed by your doctor. Keep taking the medicine regularly even if your condition improves. Do not self-medicate or stop the medication without your doctor's advice. Lifestyle modification is also essential in improving your condition, hence you should eat a balanced diet and exercise regularly to get the maximum benefit from the treatment. Amlozaar (5/25 mg) Tablet may make you feel dizzy or lightheaded, so be careful when standing up suddenly. It can cause sleepiness and dizziness, so avoid driving vehicles or operating machines unless you know how this medicine affects you. Amlozaar (5/25 mg) Tablet may cause swelling of your ankles which can be avoided by low salt intake and keeping your leg raised when you are sitting down.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlozaar (5/25 mg) Tablet is a combination of Amlodipine and Losartan. Amlodipine and Losartan widen the blood vessels by relaxing the heart muscles and helps in the smooth flow of blood. This combination causes a decrease in blood pressure and reduces strain on your heart.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antihypertensive combinations, Angiotensin II inhibitors with calcium channel blockers

Schedule

Schedule H

Drugs, H., 2021. Losartan: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 15 September 2021].

https://medlineplus.gov/druginfo/meds/a695008.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Losartan. [online] Available at: < [Accessed 24 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Losartan>

Medicines.org.uk. 2021. Amlodipine 5mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 3 August 2021].

https://www.medicines.org.uk/emc/product/4717/smpc#gref>

Drugs, H., 2021. Amlodipine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 15 September 2021].

https://medlineplus.gov/druginfo/meds/a692044.html>

Medicines.org.uk. 2021. Losartan potassium 50 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 24 June 2021].

https://www.medicines.org.uk/emc/product/7061/smpc>
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Information on this page was last updated on 28 Sep 2021

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