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Amitop 50 MG Tablet SR
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Amitop 50 MG Tablet SR

Manufactured byTas Med (India) Pvt. Ltd.
ContainsAmitriptyline
Description
Amitop 50 MG Tablet SR is an effective medicine used for the prevention of migraine attacks. It can also be used to treat neuropathic pain (nerve pain that may be caused by nerve damage or chronic diseases such as diabetes) in adults. It is also used to treat depression in adult patients.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Amitop 50 MG Tablet SR

Goldep 50 MG Tablet SR
Glenmark Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Amitop 50 MG Tablet SR

  • Headache
  • Nausea and Vomiting
  • Constipation or diarrhea
  • Blurred vision
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Unexpected weight gain or loss
  • Chest pain and discomfort
  • Shortness of breath
  • Weakness in one side of the body
  • Slurred speech
  • Seizures
  • Decreased sexual urge
  • Unusual bleeding

Uses of Amitop 50 MG Tablet SR

What is it prescribed for?

  • Migraine Prevention
  • Bed wetting
  • Neuropathic pain
  • Depression
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to amitriptyline or any other inactive ingredients present in the formulation.

Monoamine oxidase inhibitors

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.

Heart attack

This medicine is not recommended for use in patients who have had an episode of heart-attack in recent times or recovering from it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Hypotension

Use of this medicine may increase the risk of fall in blood pressure, and hence, caution is advised. Regular monitoring of blood pressure is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver disease

This medicine should be used with caution in patients who are suffering from liver diseases due to the increased risk of adverse effects. Regular monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Kidney disease

This medicine should be used with caution in patients who are suffering from kidney diseases due to the increased risk of adverse effects. Regular monitoring of the kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Bipolar disorder

This medicine should be used with extreme caution in patients suffering from bipolar disorder due to the increased risk of worsening the patient's condition. Consult your doctor and report the incidence of bipolar depression or mania before receiving this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. This risk is especially higher in young adult patients. Patients should be closely monitored for any change in mood or behavior. Report any such incidence to the doctor so that counseling and monitoring of progress can be performed at regular intervals. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Benign prostatic hyperplasia

This medicine should be used with caution if you have an enlarged prostate gland due to the increased risk of worsening the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Other medicine

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Surgery

The use of this medicine is not recommended if you are planning to undergo surgery in the near future. Consult your doctor in this regard so that it can be discontinued properly.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Cisapride

Clozapine

Fluoxetine

Linezolid

Ondansetron

Selegeline

Phenylephrine

Disease interactions

Heart Disease

This medicine should be used with caution in patients suffering from heart disease like heart failure, stroke, heart block, etc due to the increased risk of adverse effects. A fall in blood pressure, changes in the pulse, dizziness and other associated complications should be reported to the doctor on priority. It is advised to not take this medicine if the patient has recently suffered a heart attack. An alternative treatment option should be considered in some cases based on the clinical condition.

Pheochromocytoma

This medicine should be administered with extreme caution in patients suffering from Pheochromocytoma, the risk of severe to fatal change in blood pressure is very high. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients who are suffering from seizures due to the increased risk of worsening of the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution if you have diabetes as the risk of changes in blood sugar levels are very high. You should get your blood sugar levels checked more frequently while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Glaucoma

This medicine should be used with caution if you have glaucoma. Use of this medicine can worsen the symptoms of both closed and open-angle glaucoma. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as instructed by the doctor. Follow all the labeled instructions while taking this medicine. Ensure that the right quantity of medicine is consumed for the prescribed duration only. Initial use may worsen the symptoms of depression and it may take up to 20-30 days for any improvement to happen. Usage should not be stopped abruptly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine is believed to work by increasing the concentration of norepinephrine and serotonin which are the two primary chemical messengers in the brain.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Tricyclic antidepressants

Schedule

Schedule H

Amitriptyline: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682388.html

Amitriptyline - DrugBank [Internet]. Drugbank.ca. 2017 [cited 25 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB00321
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Information on this page was last updated on 14 Apr 2020

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