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Aminophylline 250 MG Injection
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Aminophylline 250 MG Injection

Manufactured byGlaxosmithkline Pharmaceuticals Ltd.
ContainsAminophylline
Description
Aminophylline 250 MG Injection is a very effective bronchodilator medicined used to prevent and treat wheezing, shortness of breath, chest tightness associated with lung diseases like asthma, chronic bronchitis, emphysema, chronic obstructive pulmonary disorder (COPD), etc.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Aminophylline 250 MG Injection

  • Increased/Irregular heart rate
  • Convulsions (seizures)
  • Allergic Skin Reaction
  • Stomach discomfort and pain
  • Diarrhea
  • Headache
  • Sleeplessness
  • Swelling of ankles or feet
  • Yellowing of skin and eyes
  • Increased urination frequency
  • Twitching and unusual movement of muscles
  • Pain at the injection site

Uses of Aminophylline 250 MG Injection

What is it prescribed for?

  • Asthma (Acute)
  • Bronchospasm
  • Chronic obstructive pulmonary disease (COPD)
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use by women who are breastfeeding unless necessary. Consult your doctor and discuss the risks associated with use before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to aminophylline, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use by women who are breastfeeding unless necessary. Consult your doctor and discuss the risks associated with use before taking this medicine.
General warnings

Other diseases

Report the instance of any disease of the heart and blood vessels, brain, thyroid glands, etc to the doctor before receiving this medicine. This medicine should be used with caution and any disease worsening symptom should be reported to the doctor immediately. An alternative treatment option should be considered in some cases based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Smoking

This medicine tends to be less effective if you smoke or consume tobacco products. Avoid or limit the uptake of tobacco products while taking this medicine.

Caffeine

Consumption of caffeine while taking this medicine may cause certain side effects to appear. Avoid or limit the uptake of caffeine or caffeine products while taking this medicine.

Fever

This medicine should be used with caution if you have a high fever (febrile) with a headache, chills, and joint pain. Report any such instance to the doctor while taking this medicine.

Aminophylline toxicity

Use of high doses of this medicine has been associated with toxicity due to an accumulation of the medicine in the body after long term use. It is advised to measure the serum levels and withhold the dose of this medicine if toxicity symptoms are developed.

Use in the elderly

This medicine should be used with caution in the elderly as the risk of adverse effects are significantly higher.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Fluvoxamine

Lithium

Phenytoin

Propranolol

Ethinyl Estradiol

Azithromycin

Ciprofloxacin

Riociguat

Disease interactions

Peptic ulcer

This medicine should be administered with caution in patients with active peptic ulcer disease as the risk of worsening of symptoms is very high. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustment or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients who are suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients who are suffering from seizures due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart rhythm disorders

This medicine should be used with caution in a patient suffering from a heart rhythm disorder due to the increased risk of worsening of the patient's condition. Suitable clinical investigations should be performed to determine the safe and effective use of this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.
Food interactions
Avoid or limit the uptake of caffeine while taking this medicine due to the increased risk of adverse effects. Report any incidence of unusual symptoms to the doctor on priority.
Avoid consumption of tobacco and marijuana while taking this medicine. The risk of adverse effects is high even with secondhand smoking.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the muscles of the airways in the lungs. It also reduces the sensitivity of lungs to allergens that cause irritation and constriction of muscles in the chest and the lungs.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Methylxanthines

Schedule

Schedule H

Aminophylline - DrugBank [Internet]. Drugbank.ca. 2017 [cited 19 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB01223

Aminophylline | C16H24N10O4 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 19 May 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/9433#section=Top

Aminophylline: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 19 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601015.html

DailyMed - Aminophylline injection, solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 19 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=754e8580-c710-4a60-8c4e-184be3cf1f41
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Information on this page was last updated on 9 Mar 2020

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