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Ambisome 50 mg Injection
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Ambisome 50 mg Injection

Manufactured byAbbott Healthcare Pvt. Ltd.
ContainsAmphotericin B (Liposomal)
Description
Ambisome 50 mg Injection is an antifungal medicine. It is used to treat serious and life-threatening fungal infections caused by different fungal species. This medicine works by stopping the growth of fungi. Ambisome 50 mg Injection shows side effects like decreased potassium levels, nausea, vomiting, chills, diarrhoea, weakness, etc. Consult your doctor if any of these side effects do not resolve with time or worsen. Avoid receiving this medicine if you are allergic to it. Ambisome 50 mg Injection will be administered in a hospital setting by a healthcare professional. Your doctor will decide the dose and duration of treatment based on the severity of the infection. Do not self administer this medicine. Ambisome 50 mg Injection should be used with caution if you have kidney problems. Inform your doctor if you are taking any other medicines to avoid undesired effects. Inform your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Ambisome 50 mg Injection

Amphonex 50 mg Injection
Bharat Serums & Vaccines Ltd.
Amphotericin B (Cipla) 50 mg Injection
Cipla Ltd.
Hospicin B 50 mg Injection
Alkem Laboratories Ltd.
Phosome 50 mg Injection
Cipla Ltd.
Sporotar 50 mg Injection
Emcure Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Ambisome 50 mg Injection

  • Irregular heart beat
  • Fever and chills
  • Diarrhoea
  • Decreased potassium levels
  • Anaemia
  • Cough
  • Stomach pain
  • Headache
  • Pain at injection site
  • Nausea and Vomiting
  • Chest pain

Uses of Ambisome 50 mg Injection

What is it prescribed for?

  • Invasive Aspergillosis
  • Candidemia
  • Cryptococcosis
  • Febrile Neutropenia
  • Leishmaniasis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time Ambisome 50 mg Injection takes to show its action is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Ambisome 50 mg Injection remains active in your body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Ambisome 50 mg Injection has no habit-forming tendency.
  • Can this medicine be taken during pregnancy?
    As animal studies indicate that Ambisome 50 mg Injection does not harm the foetus, this medicine may be used during pregnancy upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    It is not known if Ambisome 50 mg Injection passes into the breastmilk. If you are breastfeeding, discuss all the risks and benefits associated with this medicine with your doctor before receiving it.

Allergy

Ambisome 50 mg Injection is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

As animal studies indicate that Ambisome 50 mg Injection does not harm the foetus, this medicine may be used during pregnancy upon your doctor's recommendation.

Breast-feeding

It is not known if Ambisome 50 mg Injection passes into the breastmilk. If you are breastfeeding, discuss all the risks and benefits associated with this medicine with your doctor before receiving it.
General warnings

Anaphylaxis

Ambisome 50 mg Injection may cause serious anaphylactic reactions (an allergic reaction that is serious and life-threatening if not treated immediately). An anaphylactic reaction occurs immediately after receiving any medicine you are allergic to them. Hence, your doctor will monitor you closely while administering this medicine.

Noninvasive fungal infections

Ambisome 50 mg Injection is not recommended to treat noninvasive fungal infections in people with normal neutrophil (a type of white blood cell) counts.

Infusion reactions

Ambisome 50 mg Injection may cause infusion reactions such as a headache, fever, chills, loss of appetite, nausea, vomiting, breathing problems, or dizziness with the first few doses. These reactions usually diminish with subsequent doses.

Missed Dose

As Ambisome 50 mg Injection is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

As Ambisome 50 mg Injection is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Tacrolimus

Cidofovir

Indapamide

Flucytosine

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Ambisome 50 mg Injection should be administered in a hospital setting by a qualified healthcare professional. Carefully follow all the instructions given by your doctor. Report to your doctor about all your current medications as well as your medical conditions before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Ambisome 50 mg Injection works by blocking the action of a vital component of the fungal cell membrane (protective covering). Thus it slows the growth of the fungi.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Polyenes, Antifungals

Schedule

Schedule H

Medicines.org.uk. 2021. [online] Available at: [Accessed 28 October 2021].

https://www.medicines.org.uk/emc/files/pil.1022.pdf

Drugs, H., 2021. Amphotericin B Liposomal Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 28 October 2021].

https://medlineplus.gov/druginfo/meds/a616018.html

2021. [online] Available at: [Accessed 28 October 2021].

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2019-PI-01848-1

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 28 October 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050740s016lbl.pdf
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Information on this page was last updated on 6 Mar 2023

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