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Acent-TZ Tablet

Manufactured byINTRA LABS PVT. LTD
ContainsAceclofenac (100 mg) + Tizanidine (2 mg)
Description

Acent-TZ Tablet is a combination medicine used for the treatment of acute low back pain associated with spasms in adults. It is not recommended for use in children and adolescents.

Side effects

Major & minor side effects for Acent-TZ Tablet

  • Chest pain or discomfort
  • Fever or chills
  • Nausea or Vomiting
  • Nervousness
  • Painful or burning urination
  • Unusual tiredness
  • Blurred vision
  • Flu like symptoms
  • Irregular heartbeat
  • Itching skin
  • Shortness of breath
  • Weight gain
  • Abdominal pain
  • Constipation
  • Diarrhea
  • Skin rash

Uses of Acent-TZ Tablet

What is it prescribed for?

  • Acute low back pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, gastrointestinal bleeding, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to aceclofenac, any other NSAIDs, tizanidine, or any other components present along with these medicines.

CYP1A2 inhibitors

This medicine is not recommended for use in patients receiving CYP1A2 inhibitors such as fluvoxamine due to the increased risk of severe adverse effects.

Asthma

This medicine is not recommended for use in patients suffering from asthma since it may worsen the patient's condition.

Bleeding disorder

This medicine is not recommended for use in patients with bleeding disorders due to the increased risk of excessive bleeding.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings

Hypotension

This medicine should be used with caution in patients with a known history of hypotension or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure may be required for such patients.

Renal impairment

This medicine should be used with caution in patients with a known history of renal impairment due to the increased risk of severe adverse effects. Close monitoring of renal function and appropriate dose adjustments may be necessary based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients with a known history of liver impairment due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is recommended for such patients. Therapy may need to be discontinued based on the clinical condition.

Sedation

This medicine should be used with caution in patients receiving sedatives since it may increase the sedative effects of such medications. Any unusual symptoms should be reported to the doctor on priority. Appropriate dose adjustments should be done under your doctor's supervision.

Drowsiness

This medicine may cause drowsiness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you suffer from drowsiness during treatment with this medicine.

Gastro-intestinal bleeding

This medicine should be used with extreme caution due to the increased risk of severe gastrointestinal bleeding, especially with prolonged use. This risk is significantly higher in the elderly population and in patients with a history of gastrointestinal diseases. Report any unusual symptoms such as blood in the stool or vomit to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Heart surgery

This medicine is not recommended for use before or after a CABG (coronary artery bypass graft) procedure since it may worsen the patient's condition.

Asthma

This medicine is not recommended for use in patients with a known history of asthma or family history of asthma due to the increased risk of worsening of the patient's condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, gastrointestinal bleeding, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amlodipine

Atenolol

Citalopram

Clozapine

Lithium

Amiodarone

Digoxin

Corticosteroids

Antihypertensives

Benazepril

Disease interactions

Renal Dysfunction

This medicine should be used with caution in patients with a known history of renal dysfunction due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hypotension

This medicine should be used with caution in patients with a known history of hypotension or patients predisposed to hypotension due to the increased risk of hypotensive episodes. Appropriate dose adjustments and close monitoring of blood pressure are recommended for such patients.

Liver Disease

This medicine should be used with caution in patients with a known history of liver diseases due to the increased risk of liver injuries. Liver function should be assessed before initiating treatment. Close monitoring of liver function may be necessary during treatment with this medicine. Therapy may need to be discontinued based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Consumption of caffeine may increase the effects of this medicine. This may cause side effects such as drowsiness, dizziness, lightheadedness, fainting, irregular heartbeat, etc. Hence, you are advised to avoid the consumption of caffeine during treatment with this medicine.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken immediately after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Aceclofenac works by reducing the formation of certain substances in the body that cause pain and swelling. Tizanidine acts on the nervous system and reduces muscle spasms, allowing the muscles to relax. The combination is thus effective in treating acute low back pain associated with spasms.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Skeletal muscle relaxants

Schedule

Schedule H

DailyMed - Clanza CR- aceclofenac tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 2 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3

[Internet]. 2017 [cited 2 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/32903#Productinfo

DailyMed - Tizanidine Hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 30 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1fa26940-3778-4758-811e-3e1531d919df

EMC [Internet]. 2017 [cited 30 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/22602

Tizanidine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 30 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601121.html

Tizanidine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 30 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00697
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Information on this page was last updated on 2 Oct 2017

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