Recently Answered Questions on GLUCAGON

When sugar is low with diabetic patient why don't alpha cells secrete glucagon? If one get diabetes both b cells and alpha cells got damaged?

I'm on medications (oral tablets, Ryzodeg insulin etc) for diabetic control. I often find the sugar readings increase dramatically (fasting of 115 in summer and goes to 210 in winter, for the same food and exercises). Often I need to increase dosage of insulin to 3 times plus compared to summer time dosage of 12 units in the afternoon. However I've not increased Metformin dosage, remains at 500 mg 1-0-1. Recently I read an article which stated that in winter to keep the body warm, the metabolism increases, which in turn reduces blood sugar levels and in turn liver releases glucagon into blood Will my problem be solved by enhancing the dosage of Metformin?

Past week I have been wakening up early in the morning with the following symptoms. -palpitations -sweating and clammy -shaky -nervousness and pale All this symptoms go when I eat food. Over all health last 3 months, I have lost unexplained weight of around 10-11 kg And loss of appetite. O/E - Pulse: 116 BP: 127/65 TEMP: 37.6 RESP: 13 Blood sugar: 2.5 I'm a non diabetic don't drink or smoke and not on anything to lower blood sugar or any medication. Recent weight: 54kg Height: 5.6 ft I done a home fasting 72 hour test and at 25 hours my blood sugar dropped to 2.2 I can prevent this with glucagon IM and what condition could be causing this - cancer ???

Sir, from last one year I  can't do any kind of physical activity n  exercises  even climbing the stairs n holding my hand up is difficult for me .If overexerted it will lead to fainting . I m also experiencing weakness,fatigue, dizziness throughout a day since last one year and  also lost 17 kg weight . All these symptoms increase during morning . I had taken lot of multivitamins and healthy balanced diet but it is of no use . I had undergone following blood test -      CBC+PS Thyroid (T3, T4, TSH) Liver function tests, Sgot ,sgpt Kidney function tests USG of abdomen Vitamin d3 etc etc all of these came to be  normal . I had to eat many times a day especially ( carbohydrates) to reduce these symptoms temporarily .,if meal skipped then these symptoms increases significantly . I had tried hydrocortisone , glucagon tablets for 4-5 days in may 2018  which reduces these symptoms to great extent. ye sab symptoms mujhe last year  (mar-aug 2017 )low carb diet plus heavy exercises krne