Recently Answered Questions on Colistin

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67 years old with MDR UTI infection

My father is suffering from UTI.. He is infected with MDR pseudomonas aeruginosa. Doctors tried with antibiotics like - imipenem, tigicycline, morepen, colistin.. With colistin, his creatinine level increased to 3.6...so doctors stopped colistin.. After colistin administration, his urine culture did not show any growth.. However, he is still having mild fever (99-100.5)..per doctor, infection might still exist.. He is now taking oral fosfomycin twice weekly for 3 weeks. Any further option here.
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Loose motions

1.5 yr old baby is having loose motions 8 times since morning not responsible to powergyl and zifi. Otherwise child active and no dehydration is present. Today doctor started syp colistin. Is colistin safe in kids. Pls tell wether I should start or not
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Loose motions

My baby is suffering from loose motions from past three days yesterday doctor gave prilobiotic and colistin sulphate oral suspension how much time will he take to recover are these medications safe baby is 5.5 months old
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Klebsiella pneumonia

The patient has klebsiella pneumonia in his lungs. The bacteria is resistant to most of the antibiotics other than colistin and amikacin as per the BAL culture report. The report also says it's carbepenamase resistant. The colony count is 10'4 cfu/ml. Please explain
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Eschershia coli in semen

I got infected with ESBL ans carbepenum positive E.coli infection. This is only resistant to tygecyline and colistin. I was admitted to hospital and given tygecyline through IV fir 3 days by urologist. Now which is the correct antibiotics to take for treatment of this infection. It is bacterial prostatitis. Is it treatable.
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Pedeatric.,motion control, wight gain

My baby 3mnts,(62days)lbw baby wight ,brest feeding,for 2-2:30hrs 60ml-,75ml baby having. no wight gaining(500grms increase in 36days),presnt wight 1.5kg.. actualy last 30 days baby motion daily minm 7-10 tyms.sporlac,ecorom,colistin sulphate oral,entrogermia tub, zerolac &nusobee no use.baby some times lethargy.. few days bak chek for 2d eco.. impression--poor eco window.. small O.S.A.S.D.WITH L➡️R shunt
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Pain in lower abdomen

I underwent Proctocolectomy+IPAA+covering loop ileostomy on 1st November..After that I developed UTI(55-60 pus cells/hpf),urine c/s report-colistin is sensitive while the rest of them are resistant..Had the following medicines-Niftran 100 mg,Augmentin 625,Citralka syrup..After that did urine test which showed 1-2 pus cells/hpf..Was having pain in lower abdomen so doc gave medDid USG which showed significant post void residue-140cc..Foley catheter was placed & removed after 4 days..Still having heaviness & at times Im getting a sharp pain(as if needle is being pricked)in lower abdomen.Is the pain due to surgery or due to Urinary problem?Kindly answer..I'm disturbed..Please help me..
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For unconscious brain ,no movement body

My father had a brain surgery[csf ottorhea] 5 months ago,he has an infection [pseudomonas ] come from hospital which couldn't cured after giving lots of antibiotics which are sensitive shown in csf culture, but no improvement seen.approx 15 days after operation there seen a swelling in brain,and my father became unconscious and breathing problems.doctors adviced to do MRI . MRI shows there is hydrocephalus developed in brain.then doctors adviced to do Vp shunt operation.after operation he is liitle bit consious and we discharge him from hospital.but after some days he again becomes unconscious and infection is still there..now what should we do? Antibiotics  given for infection are as follows; Meopenum 1.polymyxin 2.minocycline 3.vancomycin 4.micafungene 5.amphotericin 6.zavicefta 7.colistin 8.fosfomycin
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Urinal infection after 23 years of renal

My father age 64 years has undergone renal transplant in 1993. My uncle had donated his kidney to my father. He took good care of his transplanted kidney. But due to heavy medication his arteries are getting blocked due to calcification . After renal transplant he had undergone by pass surgery and operated for his lower limbs . Recently in September 2016 his BP rose to 210 -120 . He was admitted to hospital where he was treated for BP after few weeks he stopped urinating again admitted but this time he was catherised and diagnosed with clots in bladder for which he was irrigated heavily. His creatinine 2 now. Presently problem is that he is having hernia near kidney and due to urinal infection he can't opt for surgery. Urine culture is showing significant growth in colistin ( sensitive) and other component as resistance . Puss count is 3-4 .and Colony count is 10^5 What should we do . He is having antibiotics for last 8 weeks firstly via IV than Injections now orally.
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Organism: Klebsiella pneumoniae ssp pneu

Kindly see the below report and please tell if there is anything serious. Reference: S -Sensitive R -Resistant I -Intermediate Organism: Klebsiella pneumoniae ssp pneumoniae Antibiotic Sensitivity MIC Value Amikacin R >=64 Amoxicillin/Clavulanic acid R >=32 Ampicillin R >=32 Cefixime R >=4 Cefoxitin R >=64 Ceftazidime R >=64 Ceftriaxone R >=64 Ciprofloxacin R >=4 Ertapenem R >=8 Fosfomycin S 32 Gentamicin R >=16 Nalidixic acid R >=32 Nitrofurantoin R 256 Ofloxacin R >=8 Piperacillin / Tazobactam R >=128 Ticarcillin R - Trimethoprim / Sulfamethoxazole R >=320 Colistin S - Ceftriaxone EDTA Sulbact Please see the above report.
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