My brother has bipolar disorder.

He has this medical condition near abt 7 yrs now. Almost every alternate year he goes through some sort of difficult medical condition when he does nt understand what is reality, he stops eating ,sleeping, and he went through some sort of extreame trigger or attack, completely loose his identity as a normal human being and it repeats. We always need to admit him to a medical centre as he becomes unmanageable, disoriented , and very agressive. After prolonged 3-4 months of medication slowly he comes back to his normal senses and then he stops cooperating regarding his treatment. Does not take medicines and discontinue the treatment, his family tried everything but they can not make him continue the treatment. Hence within a year again he goes back to the same difficult condition all of sudden. Please advise how can we make him live a normal life and continue the treatment to avoid this sort of difficult phase of his life. Currently he is getting treated by a physctiartist locally.