Please Stop it It is not good for health in long term use And it doesn't work permanently for pimples Instead.... Do following.... Apply own saliva in the morning on waking up to pimples, keep it for 10 minutes and wash with water Afterwards Apply Aloe Vera gel by Patanjali Keep it for 10 minutes and wash with water Apply milk and turmeric regularly at night, keep it for 20 minutes and wash Take Berberis aquifolium Q Liquid Homeopathic medicine 10 drops in 25 ml water three times a day for 3 months Eugenia Q Homeopathic medicine 10 drops in 25 ml water three times a day for 3 months And ...................... Sulphur 30 Homeopathic medicine 4 drops on tongue directly Twice a day for 3 weeks only..... If pus is formed Reconsult after 15 days

Isotane which contains Isotretinoin isn't known to have any affect on the menstrual cycle.